2,6-Dichlorophenol

2,6-Dichlorophenol

SCHEMBL5320190

O=C1C=CC(=Nc2ccc(O)cc2)C=C1.Oc1c(Cl)cccc1Cl.[NaH]

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TXNRD1 Q16881 1/20 0.61
TXNRD3 Q86VQ6 1/20 0.61
TXNRD2 Q9NNW7 1/20 0.61
GRIN2D O15399 2/20 0.36
GRIN3B O60391 2/20 0.36
GRIN1 Q05586 2/20 0.36
GRIN2A Q12879 2/20 0.36
GRIN2B Q13224 2/20 0.36
GRIN2C Q14957 2/20 0.36
GRIN3A Q8TCU5 2/20 0.36
KDM4E B2RXH2 4/20 0.35
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
MAPT P10636 3/20 0.35
NPC1 O15118 2/20 0.35
MITF O75030 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,6-Dichlorophenol SCHEMBL1030875 0.98 TXNRD1 (0.63) TXNRD1TXNRD3TXNRD2GRIN2DGRIN3B
SCHEMBL1046225 0.87 TXNRD1 (0.53) TXNRD1TXNRD3TXNRD2GRIN2DGRIN3B
SCHEMBL901181 0.87 TXNRD1 (0.56) TXNRD1TXNRD3TXNRD2KDM4EMEN1
SCHEMBL35153 0.85 TXNRD1 (0.58) TXNRD1TXNRD3TXNRD2KDM4EMEN1
SCHEMBL4886981 0.84 TXNRD1 (0.57) TXNRD1TXNRD3TXNRD2GRIN2DGRIN3B
SCHEMBL21358790 0.83 TXNRD1 (0.58) TXNRD1TXNRD3TXNRD2KDM4EMEN1
Ammonia Solution, Strong SCHEMBL11281990 0.83 TXNRD1 (0.56) TXNRD1TXNRD3TXNRD2KDM4EMEN1
SCHEMBL21192750 0.83 TXNRD1 (0.56) TXNRD1TXNRD3TXNRD2KDM4EMEN1
SCHEMBL11318738 0.83 TXNRD1 (0.56) TXNRD1TXNRD3TXNRD2KDM4EMEN1
Ammonia Solution, Strong SCHEMBL10606612 0.83 TXNRD1 (0.56) TXNRD1TXNRD3TXNRD2KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007109242-A2 COLOR INDICATOR FOR HALAMINE TREATED FABRIC MILLIKEN & COMPANY (US) 2007-09-27 WO claimed
US-20070218562-A1 Color indicator for halamine treated fabric MILLIKEN & COMPANY 2007-09-20 US claimed
WO-2007109242-A2 COLOR INDICATOR FOR HALAMINE TREATED FABRIC MILLIKEN & COMPANY (US) 2007-09-27 WO disclosed
US-20070218562-A1 Color indicator for halamine treated fabric MILLIKEN & COMPANY 2007-09-20 US disclosed