Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 8/20 | 0.56 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.55 |
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13229742 | 0.90 | SLC18A3 (0.54) | SLC18A3FUCA1GBA1FAAH | |
| SCHEMBL2796545 | 0.90 | SLC18A3 (0.54) | SLC18A3FUCA1GBA1FAAH | |
| SCHEMBL3910954 | 0.88 | SLC18A3 (0.56) | SLC18A3FAAH | |
| SCHEMBL13229592 | 0.88 | KDM4E (0.61) | SLC18A3FUCA1ALDH1A1LMNAKMT2A | |
| SCHEMBL2792331 | 0.88 | KDM4E (0.61) | SLC18A3FUCA1ALDH1A1LMNAKMT2A | |
| SCHEMBL2792852 | 0.87 | FUCA1 (0.63) | SLC18A3FUCA1GBA1ALDH1A1 | |
| SCHEMBL13229582 | 0.87 | FUCA1 (0.63) | SLC18A3FUCA1GBA1ALDH1A1 | |
| SCHEMBL14385505 | 0.85 | SLC18A3 (0.55) | SLC18A3FUCA1GBA1ALDH1A1S1PR1 | |
| SCHEMBL2847210 | 0.85 | L3MBTL1 (0.51) | SLC18A3FUCA1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL13229594 | 0.85 | L3MBTL1 (0.51) | SLC18A3FUCA1ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1849781-A1 | Substituted 3-Amino-4-hydroxy pyrrolidines compounds, their preparation and use as medicaments | Laboratorios del Dr. Esteve S.A. (ES) | 2007-10-31 | — | — | EP | disclosed |