Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1576901 | 0.90 | MAPK1 (0.48) | KMT2AMAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28193245 | 0.83 | MAPT (0.69) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL17187946 | 0.83 | MAPT (0.69) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL75640 | 0.83 | MAPT (0.69) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL4102019 | 0.82 | HSD17B1 (0.61) | KMT2AMAPTRAB9ASMN1; SMN2HTT | |
| SCHEMBL6956930 | 0.82 | MAPT (0.55) | KMT2AMAPTRAB9ASMN1; SMN2NPC1 | |
| Ammonia Solution, Strong SCHEMBL17180520 | 0.81 | MAPT (0.67) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27858043 | 0.81 | MAPT (0.67) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL7929382 | 0.81 | MAOB (0.47) | KMT2AMAPTRAB9ASMN1; SMN2NPC1 | |
| Nitrogen SCHEMBL27858242 | 0.79 | MAPT (0.64) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007114916-A2 | ARYLBENZYLPIPERIDINE COMPOUNDS | H. LUNDBECK A/S (DK) | 2007-10-11 | — | — | WO | disclosed |