Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48823 | 0.88 | L3MBTL1 (0.55) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27891675 | 0.86 | L3MBTL1 (0.53) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| Formaldehyde SCHEMBL2079424 | 0.84 | L3MBTL1 (0.52) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL11565077 | 0.83 | CYP26A1 (0.51) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7149157 | 0.82 | NPC1 (0.50) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7151264 | 0.82 | NPC1 (0.50) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL11540826 | 0.81 | L3MBTL1 (0.46) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL27597052 | 0.81 | EGFR (0.50) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9377377 | 0.79 | POLB (0.47) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL2367221 | 0.78 | POLB (0.56) | L3MBTL1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007114916-A2 | ARYLBENZYLPIPERIDINE COMPOUNDS | H. LUNDBECK A/S (DK) | 2007-10-11 | — | — | WO | disclosed |
| US-5403934-A | Heterocyclic compounds | BURROUGHS WELLCOME CO. (US) | 1995-04-04 | — | — | US | disclosed |
| WO-1991013873-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-19 | — | — | WO | disclosed |
| EP-0447164-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-18 | — | — | EP | disclosed |