Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | PADI4 | Q9UM07 | 11/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316800 | 0.81 | PTGER4 (0.49) | CNR2PTGER4 | |
| SCHEMBL5316334 | 0.80 | CNR2 (0.52) | CNR2PTGER4 | |
| SCHEMBL5315360 | 0.80 | ITK (0.43) | CNR2PTGER4 | |
| SCHEMBL5315618 | 0.78 | PTGER4 (0.51) | CNR2PTGER4 | |
| SCHEMBL5318297 | 0.77 | CNR2 (0.51) | CNR2PTGER4 | |
| SCHEMBL5319931 | 0.74 | HRH3 (0.49) | HRH3CNR2PTGER4 | |
| SCHEMBL5315353 | 0.69 | HRH3 (0.42) | HRH3PADI4PTGER4 | |
| SCHEMBL2886424 | 0.64 | HRH3 (1.00) | HRH3 | |
| SCHEMBL5881837 | 0.63 | CNR2 (0.81) | CNR2 | |
| SCHEMBL2883718 | 0.63 | HRH3 (0.67) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069053-A1 | BENZIMIDAZOLE ANTAGONISTS OF THE H-3 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-06-21 | — | — | WO | claimed |
| WO-2007069053-A1 | BENZIMIDAZOLE ANTAGONISTS OF THE H-3 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-06-21 | — | — | WO | disclosed |