Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 18/20 | 1.00 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14566415 | 0.96 | PTH1R (0.92) | PTH1RCCKBR | |
| SCHEMBL5329868 | 0.92 | PTH1R (0.85) | PTH1RCCKBR | |
| SCHEMBL5494976 | 0.91 | PTH1R (0.84) | PTH1RCCKBRPTGIR | |
| SCHEMBL5323795 | 0.89 | PTH1R (0.79) | PTH1RCCKBRPTGIR | |
| SCHEMBL14566393 | 0.88 | PTH1R (0.79) | PTH1R | |
| SCHEMBL14566320 | 0.87 | PTH1R (0.77) | PTH1RCCKBRPTGIR | |
| SCHEMBL5320137 | 0.84 | PTH1R (0.72) | PTH1RCCKBR | |
| SCHEMBL5326270 | 0.84 | PTH1R (0.75) | PTH1RCCKBR | |
| SCHEMBL5280948 | 0.81 | PTH1R (0.76) | PTH1RCCKBR | |
| SCHEMBL5320304 | 0.81 | PTH1R (0.81) | PTH1RCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006129120-A9 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-03-22 | — | — | WO | disclosed |
| WO-2006129120-A2 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2006-12-07 | — | — | WO | disclosed |