Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.37 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.31 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.31 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GSR | P00390 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.30 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Serine SCHEMBL6666261 | 0.87 | SLC7A5 (0.38) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| Serine SCHEMBL5698241 | 0.86 | SLC7A5 (0.33) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL599033 | 0.86 | SLC7A5 (0.41) | SLC7A5SLC15A1 | |
| Serine SCHEMBL348967 | 0.83 | SLC7A5 (0.52) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| Serine SCHEMBL1064689 | 0.82 | SLC1A1 (0.43) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| Serine SCHEMBL12500509 | 0.79 | SLC1A1 (0.41) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| Serine SCHEMBL3628164 | 0.79 | SLC1A1 (0.41) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| Serine SCHEMBL418634 | 0.79 | PTGS1 (0.48) | SLC1A1GRIK1GRIK2GSRPTGS1 | |
| Serine SCHEMBL3961258 | 0.79 | SLC1A5 (0.36) | SLC1A1GRIK1GRIK2GSRPTGS1 | |
| Valine SCHEMBL5320793 | 0.78 | SLC7A5 (0.58) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109963870-A | ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES | 艾伯维公司 | 2019-07-02 | — | — | CN | disclosed |
| CN-109641962-A | anti-B7-H3 antibodies and antibody drug conjugates | 艾伯维公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-109562168-A | anti-CD 98 antibodies and antibody drug conjugates | 艾伯维公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109562170-A | anti-CD 98 antibodies and antibody drug conjugates | 艾伯维公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109562169-A | anti-CD 98 antibodies and antibody drug conjugates | 艾伯维公司 | 2019-04-02 | — | — | CN | disclosed |
| WO-2007103288-A2 | ENGINEERED ANTIBODY DRUG CONJUGATES | SEATTLE GENETICS, INC. (US) | 2007-09-13 | — | — | WO | disclosed |