SCHEMBL599033

SCHEMBL599033

CC(C)[C@H](N)C(=O)OC(=O)CN

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.41
SLC15A1 P46059 1/20 0.33
DPP4 P27487 2/20 0.32
FAP Q12884 1/20 0.31
DPP8 Q6V1X1 1/20 0.31
DPP9 Q86TI2 1/20 0.31
DPP7 Q9UHL4 1/20 0.31
PSMB5 P28074 1/20 0.31
LAP3 P28838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Serine SCHEMBL5320795 0.86 SLC7A5 (0.39) SLC7A5SLC15A1
SCHEMBL5320796 0.85 SLC7A5 (0.33) SLC7A5
SCHEMBL442281 0.85 SLC7A5 (0.30) SLC7A5
SCHEMBL1535416 0.84 SLC7A5 (0.42) SLC7A5SLC15A1DPP4FAPDPP8
SCHEMBL542262 0.84 SLC7A5 (0.42) SLC7A5SLC15A1DPP4FAPDPP8
SCHEMBL15658562 0.84 SLC7A5 (0.42) SLC7A5SLC15A1DPP4FAPDPP8
SCHEMBL1537296 0.82 GRIN2D (0.33) SLC7A5
SCHEMBL186138 0.82 GRIN2D (0.33) SLC7A5
SCHEMBL1537300 0.82 DPP4 (0.40) DPP4DPP8DPP9DPP7
SCHEMBL1537380 0.82 DPP4 (0.40) DPP4DPP8DPP9DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120123097-A1 RICIN A CHAIN MUTANTS LACKING ENZYMATIC ACTIVITY AS VACCINES TO PROTECT AGAINST AEROSOLIZED RICIN VITETTA ELLEN S (US) 2012-05-17 US claimed
US-8114611-B2 Affinity chromatography matrices and methods of making and using the same MILLIPORE CORPORATION (US) 2012-02-14 US claimed
US-20110105730-A1 AFFINITY CHROMATOGRAPHY MATRICES AND METHODS OF MAKING AND USING THE SAME MILLIPORE CORPORATION (US) 2011-05-05 US claimed
US-20100063261-A1 Affinity chromatography matrices and methods of making and using the same MILLIPORE CORPORATION (US) 2010-03-11 US claimed
EP-1974215-A2 AFFINITY CHROMATOGRAPHY MATRICES AND METHODS OF MAKING AND USING THE SAME MILLIPORE CORPORATION (US) 2008-10-01 EP claimed
US-20070207500-A1 Affinity chromatography matrices and methods of making and using the same MILLIPORE CORPORATION (US) 2007-09-06 US claimed
WO-2007081851-A2 AFFINITY CHROMATOGRAPHY MATRICES AND METHODS OF MAKING AND USING THE SAME MILLIPORE CORPORATION (US) 2007-07-19 WO claimed
US-5545621-A Glutathione S-transferase-activated compounds TERRAPIN TECHNOLOGIES, INC. (US) 1996-08-13 US claimed
US-11224647-B2 Safe potent single platform vaccine against Tier 1 select agents and other pathogens THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-01-18 US disclosed
US-10837027-B2 Further improved AAV vectors produced in insect cells UNIQURE IP B.V. (NL) 2020-11-17 US disclosed
US-20190322702-A1 Tricalcium Phosphate Binding Peptides And Uses Thereof ALVAREZ, LUIS 2019-10-24 US disclosed
US-20190240310-A1 SAFE POTENT SINGLE PLATFORM VACCINE AGAINST TIER 1 SELECT AGENTS AND OTHER PATHOGENS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-08-08 US disclosed
US-10329327-B2 Tricalcium phosphate binding peptides and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2019-06-25 US disclosed
EP-3490594-A1 SAFE POTENT SINGLE PLATFORM VACCINE AGAINST TIER 1 SELECT AGENTS AND OTHER PATHOGENS The Regents of the University of California (US) 2019-06-05 EP disclosed
US-5196321-A Gene expression; splitting with protease MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1993-03-23 US disclosed
US-5132213-A Peptide fusion for genetic engineering and protein synthesis MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1992-07-21 US disclosed
US-5093242-A Ubiquitin-protein fusions, stability MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1992-03-03 US disclosed
EP-0408661-A1 METHODS OF GENERATING DESIRED AMINO-TERMINAL RESIDUES IN PROTEINS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1991-01-23 EP disclosed
WO-1989009829-A2 METHODS OF GENERATING DESIRED AMINO-TERMINAL RESIDUES IN PROTEINS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1989-10-19 WO disclosed
EP-0324789-A1 METHODS OF REGULATING METABOLIC STABILITY OF PROTEINS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1989-07-26 EP disclosed