Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.52 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.52 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.52 |
| ▸ | AKT1 | P31749 | 2/20 | 0.43 |
| ▸ | AKT2 | P31751 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320273 | 0.96 | DPP4 (0.52) | DPP4DPP8DPP9AKT1AKT2 | |
| SCHEMBL5337653 | 0.93 | DPP4 (0.49) | DPP4DPP8DPP9AKT1AKT2 | |
| SCHEMBL5321406 | 0.86 | AKT1 (0.49) | DPP4DPP8DPP9AKT1AKT2 | |
| SCHEMBL5318881 | 0.82 | DPP4 (0.48) | DPP4DPP8DPP9AKT1AKT2 | |
| Hydrochloric Acid SCHEMBL5344135 | 0.82 | DPP4 (0.47) | DPP4DPP8DPP9AKT1AKT2 | |
| SCHEMBL5336486 | 0.81 | AKT1 (0.39) | DPP4DPP8DPP9AKT1AKT2 | |
| SCHEMBL5344598 | 0.80 | KMT2A (0.53) | DPP4DPP8DPP9AKT1AKT2 | |
| SCHEMBL5352678 | 0.79 | AKT1 (0.43) | DPP4DPP8DPP9AKT1AKT2 | |
| SCHEMBL5341559 | 0.79 | DPP4 (0.45) | DPP4DPP8DPP9AKT1AKT2 | |
| SCHEMBL5321252 | 0.78 | DPP4 (0.54) | DPP4DPP8DPP9ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | claimed |
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | disclosed |