Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | AKT1 | P31749 | 4/20 | 0.48 |
| ▸ | AKT2 | P31751 | 4/20 | 0.48 |
| ▸ | MGAM | O43451 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SI | P14410 | 2/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321406 | 0.91 | AKT1 (0.49) | KMT2AAKT1AKT2ALDH1A1USP2 | |
| SCHEMBL5325683 | 0.91 | AKT1 (0.51) | KMT2AAKT1AKT2GAAALDH1A1 | |
| SCHEMBL5343644 | 0.88 | GRIN1 (0.46) | KMT2AAKT1AKT2MGAMGAA | |
| SCHEMBL5342012 | 0.85 | AKT1 (0.44) | KMT2AAKT1AKT2GAAALDH1A1 | |
| SCHEMBL5320273 | 0.84 | DPP4 (0.52) | KMT2AAKT1AKT2MEN1CYP1A2 | |
| SCHEMBL5345880 | 0.83 | PTGS2 (0.55) | AKT1AKT2NR1I3 | |
| SCHEMBL5349048 | 0.83 | AKT1 (0.48) | KMT2AAKT1AKT2GAAALDH1A1 | |
| SCHEMBL5341386 | 0.82 | AKT1 (0.49) | AKT1AKT2GAAALDH1A1RAB9A | |
| SCHEMBL5322231 | 0.81 | AKT1 (0.48) | AKT1AKT2GAAALDH1A1CYP1A2 | |
| SCHEMBL5352678 | 0.81 | AKT1 (0.43) | KMT2AAKT1AKT2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | claimed |
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | disclosed |