Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.50 |
| ▸ | MPO | P05164 | 8/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3739229 | 0.74 | PTPN1 (0.51) | PTPN1PTPN2 | |
| SCHEMBL31744625 | 0.74 | GPR84 (0.71) | GPR84MPOTSHRSLC6A4HTR2A | |
| SCHEMBL5317466 | 0.72 | HDAC1 (0.45) | PTPN1PTPN2 | |
| SCHEMBL7592726 | 0.71 | PTPN1 (0.61) | PTPN1PTPN2 | |
| SCHEMBL7193731 | 0.71 | PTPN1 (0.64) | PTPN1PTPN2 | |
| SCHEMBL3742965 | 0.71 | PTPN1 (0.56) | PTPN1PTPN2 | |
| SCHEMBL3738325 | 0.71 | PTPN1 (0.56) | PTPN1PTPN2 | |
| SCHEMBL7187515 | 0.70 | PTPN1 (0.57) | PTPN1PTPN2 | |
| SCHEMBL31744628 | 0.70 | GPR84 (0.73) | GPR84MPOTSHRSLC6A4HTR2A | |
| SCHEMBL18383118 | 0.70 | GPR84 (1.00) | GPR84MPOTSHRSLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007081755-A2 | INDOLE-BENZIMIDAZOLE AND INDAZOLE INHIBITORS OF TYROSINE PHOSPHATASES | METABASIS THERAPEUTICS, INC. (US) | 2007-07-19 | — | — | WO | claimed |