Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2953354 | 0.85 | CACNA1H (0.39) | CACNA1HCACNA1BCACNA1C | |
| SCHEMBL2954657 | 0.82 | TRPV1 (0.37) | — | |
| SCHEMBL2954663 | 0.82 | BRD9 (0.38) | — | |
| SCHEMBL5324801 | 0.77 | TRPV1 (0.46) | — | |
| SCHEMBL10232987 | 0.76 | BRD9 (0.48) | CACNA1HCACNA1BCACNA1C | |
| SCHEMBL18854481 | 0.76 | EPAS1 (0.43) | CACNA1HCACNA1BCACNA1C | |
| SCHEMBL1999920 | 0.75 | TSHR (0.41) | — | |
| SCHEMBL28695516 | 0.75 | TRPV1 (0.50) | — | |
| SCHEMBL2001037 | 0.75 | NSD2 (0.39) | — | |
| SCHEMBL956783 | 0.75 | KIF11 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007120012-A1 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2007-10-25 | — | — | WO | disclosed |