Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KHK | P50053 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6939079 | 0.86 | HPGD (0.72) | HPGDHTTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL880365 | 0.84 | ALDH1A1 (0.62) | HPGDHTTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL16589495 | 0.82 | HPGD (0.67) | HPGDHTTKDM4EALDH1A1HSD17B10 | |
| Butane SCHEMBL7847687 | 0.81 | ALDH1A1 (0.60) | HPGDHTTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL880382 | 0.80 | HPGD (0.73) | HPGDHTTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL6606040 | 0.80 | EGFR (0.48) | SMN1; SMN2LMNAHIF1A | |
| SCHEMBL30623245 | 0.80 | EGFR (0.48) | SMN1; SMN2LMNAHIF1A | |
| SCHEMBL30824255 | 0.79 | HPGD (0.67) | HPGDHTTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL1793179 | 0.79 | SMN1; SMN2 (0.60) | HPGDHTTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL17817603 | 0.76 | HPGD (1.00) | HPGDHTTKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |