Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | ESRRA | P11474 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322328 | 1.00 | ENPP2 (0.41) | ENPP2CCR2SLC22A12PTGDR2AKR1B1 | |
| SCHEMBL5323696 | 0.92 | ENPP2 (0.40) | ENPP2CCR2SLC22A12PTGDR2AKR1B1 | |
| SCHEMBL5323691 | 0.92 | ENPP2 (0.40) | ENPP2CCR2SLC22A12PTGDR2AKR1B1 | |
| SCHEMBL5318742 | 0.91 | ENPP2 (0.39) | ENPP2CCR2SLC22A12PTGDR2AKR1B1 | |
| SCHEMBL5318741 | 0.91 | ENPP2 (0.39) | ENPP2CCR2SLC22A12PTGDR2AKR1B1 | |
| SCHEMBL1045413 | 0.90 | ENPP2 (0.42) | ENPP2CCR2SLC22A12AKR1B1NPSR1 | |
| SCHEMBL1045414 | 0.90 | ENPP2 (0.42) | ENPP2CCR2SLC22A12AKR1B1NPSR1 | |
| SCHEMBL5324025 | 0.89 | NR1H2 (0.42) | ENPP2CCR2SLC22A12AKR1B1NR1H2 | |
| SCHEMBL5324030 | 0.89 | NR1H2 (0.42) | ENPP2CCR2SLC22A12AKR1B1NR1H2 | |
| SCHEMBL1050822 | 0.87 | ENPP2 (0.45) | ENPP2CCR2SLC22A12PTGDR2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786424-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | The University of Kansas (US) | 2007-05-23 | — | — | EP | claimed |
| WO-2006023704-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | UNIVERSITY OF KANSAS (US) | 2006-03-02 | — | — | WO | claimed |