Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.46 |
| ▸ | CCR8 | P51685 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28087696 | 0.88 | KDM4E (0.54) | KDM4ELMNACYP1A2CCR1CCR5 | |
| SCHEMBL11140262 | 0.83 | KDM4E (0.48) | KDM4ELMNACYP1A2CCR1CCR5 | |
| SCHEMBL30958577 | 0.77 | MAPT (0.57) | KDM4ELMNABLMSMN1; SMN2L3MBTL1 | |
| SCHEMBL1207426 | 0.77 | KDM4E (0.50) | KDM4ELMNACYP1A2CCR1CCR5 | |
| SCHEMBL11605127 | 0.77 | KDM4E (0.50) | KDM4ELMNACYP1A2CCR1CCR5 | |
| SCHEMBL31038172 | 0.77 | KDM4E (0.50) | KDM4ELMNACYP1A2CCR1CCR5 | |
| SCHEMBL28087698 | 0.76 | KDM4E (0.48) | KDM4ELMNACYP1A2CCR1CCR5 | |
| SCHEMBL10333796 | 0.75 | PRKCI (0.42) | KDM4ELMNACYP1A2CCR1CCR5 | |
| SCHEMBL858806 | 0.75 | KDM4E (0.72) | KDM4ELMNACYP1A2CCR1CCR5 | |
| SCHEMBL731647 | 0.74 | RAB9A (0.59) | KDM4ELMNACYP1A2CCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007123910-A2 | COPPER-MEDIATED FUNCTIONALIZATION OF ARYL C-H BONDS, AND COMPOUNDS RELATED THERETO | BRANDEIS UNIVERSITY (US) | 2007-11-01 | — | — | WO | disclosed |
| WO-2007123910-A2 | COPPER-MEDIATED FUNCTIONALIZATION OF ARYL C-H BONDS, AND COMPOUNDS RELATED THERETO | BRANDEIS UNIVERSITY (US) | 2007-11-01 | — | — | WO | disclosed |