⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2671575 | 0.92 | — | — | |
| Iodide SCHEMBL11348804 | 0.88 | — | — | |
| Lithium SCHEMBL7929038 | 0.88 | — | — | |
| SCHEMBL4046300 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL1170290 | 0.88 | — | — | |
| Bromide SCHEMBL11354974 | 0.88 | — | — | |
| Lithium Ion SCHEMBL1408733 | 0.85 | — | — | |
| SCHEMBL827627 | 0.85 | — | — | |
| SCHEMBL27485439 | 0.81 | — | — | |
| SCHEMBL28321420 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633241-B2 | Nebivolol and its pharmaceutically acceptable salts, process for preparation and pharmaceutical compositions of nebivolol | Forest Laboratories Holdings, Limited (BM) | 2014-01-21 | — | — | US | disclosed |
| US-20130296583-A1 | Nebivolol and its Pharmaceutically Acceptable Salts, Process for Preparation and Pharmaceutical Compositions of Nebivolol | FOREST LABORATORIES HOLDINGS UNLIMITED COMPANY (BM) | 2013-11-07 | — | — | US | disclosed |
| US-20070259950-A1 | Nebivolol and Its Pharmaceutically Acceptable Salts, Process for Preparation and Pharmaceutical Compositions of Nebivolol | TORRENT PHARMACEUTICALS LIMITED (IN) | 2007-11-08 | — | — | US | disclosed |
| EP-1741712-A2 | Nebivolol and its pharmaceutically acceptable salts, process for preparation and pharmaceutical compositions of Nebivolol | Torrent Pharmaceuticals Ltd (IN) | 2007-01-10 | — | — | EP | disclosed |
| EP-1737847-A2 | NEBIVOLOL AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS, PROCESS FOR PREPARATION AND PHARMACEUTICAL COMPOSITIONS OF NEBIVOLOL | Torrent Pharmaceuticals Ltd (IN) | 2007-01-03 | — | — | EP | disclosed |
| WO-2006025070-A2 | NEBIVOLOL AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS, PROCESS FOR PREPARATION AND PHARMACEUTICAL COMPOSITIONS OF NEBIVOLOL | TORRENT PHARMACEUTICALS LIMITED (IN) | 2006-03-09 | — | — | WO | disclosed |