Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL1408733 | 0.92 | — | — | |
| SCHEMBL2671575 | 0.92 | — | — | |
| SCHEMBL4046300 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL1170290 | 0.88 | — | — | |
| Bromide SCHEMBL11354974 | 0.88 | — | — | |
| Lithium SCHEMBL7929038 | 0.88 | — | — | |
| Iodide SCHEMBL11348804 | 0.88 | — | — | |
| SCHEMBL28435678 | 0.88 | — | — | |
| SCHEMBL5322732 | 0.85 | — | — | |
| SCHEMBL27485439 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7902357-B2 | Process for the preparation of delmopinol and derivatives thereof | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2011-03-08 | — | — | US | claimed |
| US-20100222579-A1 | Process for the Preparation of Delmopinol and Derivatives Thereof | ARTUS SURROCA JUAN JOSE | 2010-09-02 | — | — | US | claimed |
| US-20090137798-A1 | Process for the Preparation of Delmopinol and Derivatives Thereof | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2009-05-28 | — | — | US | claimed |
| EP-1948626-B1 | PROCESS FOR THE PREPARATION OF DELMOPINOL AND DERIVATIVES THEREOF | SINCLAIR PHARMACEUTICALS LTD (GB) | 2009-03-04 | — | — | EP | claimed |
| EP-1948626-A1 | PROCESS FOR THE PREPARATION OF DELMOPINOL AND DERIVATIVES THEREOF | Sinclair Pharmaceuticals Limited (GB) | 2008-07-30 | — | — | EP | claimed |
| WO-2007057681-A1 | PROCESS FOR THE PREPARATION OF DELMOPINOL AND DERIVATIVES THEREOF | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2007-05-24 | — | — | WO | claimed |
| US-8143463-B2 | Process for the preparation of delmopinol and derivatives thereof | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2012-03-27 | — | — | US | disclosed |
| US-20110092751-A1 | Process for the Preparation of Delmopinol and Derivatives Thereof | ARTUS SURROCA JUAN JOSE | 2011-04-21 | — | — | US | disclosed |
| US-7910730-B2 | Process for the preparation of delmopinol and derivatives thereof | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2011-03-22 | — | — | US | disclosed |
| US-7902357-B2 | Process for the preparation of delmopinol and derivatives thereof | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2011-03-08 | — | — | US | disclosed |
| US-20100222579-A1 | Process for the Preparation of Delmopinol and Derivatives Thereof | ARTUS SURROCA JUAN JOSE | 2010-09-02 | — | — | US | disclosed |
| US-20090137798-A1 | Process for the Preparation of Delmopinol and Derivatives Thereof | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2009-05-28 | — | — | US | disclosed |
| EP-1948626-B1 | PROCESS FOR THE PREPARATION OF DELMOPINOL AND DERIVATIVES THEREOF | SINCLAIR PHARMACEUTICALS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |
| US-20030216362-A1 | Estra-1,3,5 (10)-triene derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-11-20 | — | — | US | disclosed |
| EP-1284272-A1 | ESTRA-1,3,5(10)-TRIENE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-02-19 | — | — | EP | disclosed |
| US-4604392-A | 2-substituted benzofuran derivatives useful in treating cardiac arrhythmic, histaminic and tussive conditions | A. MENARINI S.A.S. (IT) | 1986-08-05 | — | — | US | disclosed |
| US-4485112-A | N-[(Benzofuran-2-yl)(phenyl)methyl]-alkylene diamines useful in treating arrhythmic, histaminic and tussive conditions | A. MENARINI S.A.S. (IT) | 1984-11-27 | — | — | US | disclosed |
| US-4467047-A | ISOMERIZATION CATALYST | SHELL OIL COMPANY (US) | 1984-08-21 | — | — | US | disclosed |
| US-4467048-A | ISOMERIZATION CATALYST | SHELL OIL COMPANY (US) | 1984-08-21 | — | — | US | disclosed |
| US-3988456-A | ANALGESICS, ANTITUSSIVE | DAINIPPON PHARMACEUTICAL CO., LTD. (JA) | 1976-10-26 | — | — | US | disclosed |