⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL532273 | 1.00 | — | — | |
| SCHEMBL1658940 | 0.93 | FAAH (0.54) | — | |
| SCHEMBL2163322 | 0.93 | FAAH (0.54) | — | |
| SCHEMBL7358985 | 0.91 | FAAH (0.58) | — | |
| SCHEMBL6569743 | 0.91 | FAAH (0.58) | — | |
| SCHEMBL6625727 | 0.91 | FAAH (0.58) | — | |
| SCHEMBL7288642 | 0.91 | FAAH (0.58) | — | |
| SCHEMBL7288637 | 0.91 | FAAH (0.58) | — | |
| SCHEMBL21777211 | 0.91 | FAAH (0.58) | — | |
| SCHEMBL9949863 | 0.91 | FAAH (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110933-A | AN ENZYME INHIBITOR TREATING PANCREATITIS, HEPATITIS, CHRONIC RENAL FAILURE, ENDOTOXIN SHOCK, GRAM-NEGATIVE SEPTIC SHOCK, ARTHRITIS, RESPIRATORY DISEASE, HEART DISEASE, ALLERGIC DISEASE, THROMBOSIS, ARTERIOSCLEROSIS, PAIN | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-29 | — | — | US | claimed |
| US-11154592-B2 | Method of treating Rett Syndrome (RTT) with ghrelin | KURUME UNIVERSITY (JP) | 2021-10-26 | — | — | US | disclosed |
| CN-101693736-B | Novel peptides | 寒川贤治 | 2020-09-11 | — | — | CN | disclosed |
| US-20200261541-A1 | METHODS OF TREATING MILD BRAIN INJURY | OXEIA BIOPHARMACEUTICALS, INC. (US) | 2020-08-20 | — | — | US | disclosed |
| US-20190307851-A1 | PROPHYLACTIC AND THERAPEUTIC AGENT FOR RETT SYNDROME (RTT) COMPRISING GHRELIN AS ACTIVE INGREDIENT | KURUME UNIVERSITY (JP) | 2019-10-10 | — | — | US | disclosed |
| US-20180296647-A1 | PROPHYLACTIC AND THERAPEUTIC AGENT FOR RETT SYNDROME (RTT) COMPRISING GHRELIN AS ACTIVE INGREDIENT | KURUME UNIVERSITY (JP) | 2018-10-18 | — | — | US | disclosed |
| US-9938332-B2 | Modified ghrelin peptides | Kanagawa, Kenji (JP) | 2018-04-10 | — | — | US | disclosed |
| US-20180071367-A1 | METHODS OF TREATING COGNITIVE IMPAIRMENTS OR DYSFUNCTION | OXEIA BIOPHARMACEUTICALS, INC. (US) | 2018-03-15 | — | — | US | disclosed |
| EP-3268021-A1 | METHODS OF TREATING COGNITIVE IMPAIRMENTS OR DYSFUNCTION | Oxeia Biopharmaceuticals, Inc. (US) | 2018-01-17 | — | — | EP | disclosed |
| US-20170281732-A1 | METHODS OF TREATING MILD BRAIN INJURY | OXEIA BIOPHARMACEUTICALS, INC. (US) | 2017-10-05 | — | — | US | disclosed |
| EP-0644199-A1 | Cyclic antimicrobial peptides and preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |
| US-5376634-A | Microbiocides | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-12-27 | — | — | US | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |
| EP-0486011-A2 | Pharmaceutical composition against Pneumocystis carinii | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-05-20 | — | — | EP | disclosed |
| EP-0462531-A2 | Cyclic polypeptide with antibiotic activity, process for its preparation and pure culture of a Coelomycetes strain | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-27 | — | — | EP | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |