Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 8/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | DAO | P14920 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322806 | 1.00 | FLT3 (0.63) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL5645869 | 0.82 | FLT3 (0.70) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL31060426 | 0.78 | FLT3 (1.00) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL370573 | 0.78 | FLT3 (1.00) | FLT3KDM4EMAPTDAOHPGD | |
| Methane SCHEMBL22343918 | 0.76 | FLT3 (0.96) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL5641252 | 0.75 | KDM4E (0.70) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL15178034 | 0.74 | FLT3 (0.71) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL5653870 | 0.74 | FLT3 (0.64) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL1327116 | 0.74 | FLT3 (0.64) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL5639746 | 0.74 | FLT3 (0.64) | FLT3KDM4EMAPTDAOHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007134421-A1 | 2-VINYL INDOLES, PYRIDO AND AZEPINO INDOLE DERIVATIVES, 2-ALKYNYL INDOLES, 2-ALKYNYL BENZO[b]FURANS, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2007-11-29 | — | — | WO | disclosed |