Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705215 | 0.78 | MEN1 (0.48) | MEN1KMT2ACHRNB2CHRNA4LTA4H | |
| SCHEMBL12918859 | 0.76 | MEN1 (0.46) | MEN1KMT2ACHRNB2CHRNA4LTA4H | |
| SCHEMBL1694806 | 0.75 | — | — | |
| SCHEMBL6992317 | 0.75 | TSHR (0.39) | MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL19194672 | 0.74 | TSHR (0.41) | MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL12790405 | 0.72 | MEN1 (0.42) | MEN1KMT2ATSHRALDH1A1CHRNB2 | |
| SCHEMBL5322174 | 0.71 | MEN1 (0.50) | MEN1KMT2ATSHRALDH1A1LTA4H | |
| SCHEMBL6140903 | 0.70 | — | — | |
| SCHEMBL12860905 | 0.70 | CA12 (0.41) | MEN1KMT2ATSHRCHRNB2CHRNA4 | |
| SCHEMBL27378304 | 0.70 | HSD17B10 (0.41) | MEN1KMT2ACHRNB2CHRNA4LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827423-B1 | FUNCTIONALIZED CHAIN EXTENDED INITIATORS FOR ANIONIC POLYMERIZATION | FMC CORP (US) | 2007-12-12 | — | — | EP | claimed |