Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 20/20 | 0.58 |
| ▸ | RET | P07949 | 3/20 | 0.50 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321249 | 0.82 | KDR (0.61) | KDRRET | |
| SCHEMBL5321155 | 0.74 | KDR (0.65) | KDRRET | |
| SCHEMBL2455241 | 0.73 | KDR (1.00) | KDRRET | |
| SCHEMBL12303457 | 0.73 | KDR (1.00) | KDRRET | |
| SCHEMBL2451711 | 0.73 | KDR (0.72) | KDRRET | |
| SCHEMBL12303579 | 0.73 | KDR (0.72) | KDRRET | |
| SCHEMBL12303524 | 0.73 | KDR (0.57) | KDRRETMET | |
| SCHEMBL2453105 | 0.73 | KDR (0.57) | KDRRETMET | |
| SCHEMBL5323283 | 0.72 | KDR (0.60) | KDRRET | |
| SCHEMBL5325591 | 0.72 | KDR (0.60) | KDRRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007109783-A2 | SUBSTITUTED PYRIMIDINE KINASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-09-27 | — | — | WO | disclosed |