Propylene Oxide

Propylene Oxide

SCHEMBL5324063

C1CO1.C=CCOC.CC1CO1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propylene Oxide SCHEMBL3485981 0.94
Propylene Oxide SCHEMBL1091828 0.85 ALDH1A1 (0.52) ALDH1A1TDP1
Propylene Oxide SCHEMBL253031 0.78 ALDH1A1 (0.58) ALDH1A1TDP1
Propylene Oxide SCHEMBL26962824 0.77 ALDH1A1 (0.75) ALDH1A1TDP1
Tetrahydrofuran SCHEMBL28422587 0.76 ALDH1A1 (0.38) ALDH1A1
Allylamine SCHEMBL10610839 0.76 ALDH1A1 (0.43) ALDH1A1TDP1
Allyl Alcohol SCHEMBL5668407 0.76 TSHR (0.43) ALDH1A1TDP1
Propylene Oxide SCHEMBL22362337 0.74 TDP1 (0.36) TDP1
Propylene Oxide SCHEMBL28433413 0.74 TTR (0.31)
SCHEMBL41707 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070293594-A1 Viscoelastic polyurethane foam and process for its manufacture GENERAL ELECTRIC COMPANY 2007-12-20 US claimed
EP-4705381-A1 METHOD FOR THE PREPARATION OF SILOXANES Evonik Operations GmbH (DE) 2026-03-11 EP disclosed
WO-2024227655-A1 METHOD FOR THE PREPARATION OF SILOXANES EVONIK OPERATIONS GMBH (DE) 2024-11-07 WO disclosed
US-11891486-B2 Side chain functionalized organosiloxane polymers, coating compositions and ice-phobic coatings thereof Adaptive Surface Technologies, Inc. (US) 2024-02-06 US disclosed
CN-117429747-A Packaging container and preparation method thereof 广东大地伟业环保包装科技股份有限公司 2024-01-23 CN disclosed
EP-4058505-B1 SIDE CHAIN FUNCTIONALIZED ORGANOSILOXANE POLYMERS, COATING COMPOSITIONS AND ICE-PHOBIC COATINGS THEREOF ADAPTIVE SURFACE TECH INC (US) 2023-05-24 EP disclosed
US-20230042027-A1 SIDE CHAIN FUNCTIONALIZED ORGANOSILOXANE POLYMERS, COATING COMPOSITIONS AND ICE-PHOBIC COATINGS THEREOF Adaptive Surface Technologies, Inc. 2023-02-09 US disclosed
WO-2007146351-A2 VISCOELASTIC POLYURETHANE FOAM AND PROCESS FOR ITS MANUFACTURE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2007-12-21 WO disclosed
US-20070293594-A1 Viscoelastic polyurethane foam and process for its manufacture GENERAL ELECTRIC COMPANY 2007-12-20 US disclosed
WO-2001070842-A2 POLYURETHANE FOAMS KT HOLDINGS, LLC (US) 2001-09-27 WO disclosed
EP-1116813-A1 Hydrophilic softener for textiles comprising epoxy glycol siloxane polymers and amine funtional materials DOW CORNING CORPORATION (US) 2001-07-18 EP disclosed