Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.35 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3902400 | 0.90 | KMT2A (0.41) | CA1CA2CA4KAT6AKMT2A | |
| SCHEMBL3772639 | 0.89 | MAOB (0.46) | CA1CA2CA4CA9MAPT | |
| SCHEMBL3891556 | 0.85 | KAT6A (0.43) | KAT6A | |
| SCHEMBL3767566 | 0.82 | CA1 (0.34) | CA1CA2CA4KAT6AKDM4E | |
| SCHEMBL10425119 | 0.78 | MAPT (0.45) | KDM4EKMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3892105 | 0.78 | KMT2A (0.37) | CA1CA2CA4KAT6AKDM4E | |
| SCHEMBL3897329 | 0.78 | KMT2A (0.37) | CA1CA2CA4KAT6AKDM4E | |
| SCHEMBL3895888 | 0.76 | KMT2A (0.41) | CA1CA2CA4KDM4ERXFP1 | |
| SCHEMBL3899594 | 0.76 | ALDH1A1 (0.38) | CA1CA2CA4KDM4ECA9 | |
| SCHEMBL3891422 | 0.75 | KMT2A (0.38) | CA1CA2CA4KAT6AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007114532-A1 | NOVEL CHALCONE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT, METHOD FOR PREPARATION AND USES THEREOF | INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY (KR) | 2007-10-11 | — | — | WO | disclosed |