Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL17183875 | 0.82 | TSHR (0.50) | CA2ALDH1A1TSHRKDM4ECYP3A4 | |
| SCHEMBL30435549 | 0.82 | CA2 (0.53) | CA2ALDH1A1TSHRKDM4ECYP3A4 | |
| Alcohol SCHEMBL20295436 | 0.82 | TSHR (0.50) | CA2ALDH1A1TSHRKDM4ECYP3A4 | |
| Alcohol SCHEMBL282048 | 0.82 | — | — | |
| SCHEMBL97574 | 0.82 | — | — | |
| Alcohol SCHEMBL21924398 | 0.79 | TSHR (0.46) | CA2ALDH1A1TSHRKDM4ECYP3A4 | |
| Alcohol SCHEMBL27681725 | 0.79 | — | — | |
| Dimethyl Sulfone SCHEMBL7886489 | 0.78 | — | — | |
| SCHEMBL29011136 | 0.78 | CA2 (0.47) | CA2TSHRKDM4ECYP3A4CA1 | |
| Hydrochloric Acid SCHEMBL5197032 | 0.78 | CA2 (0.47) | CA2TSHRKDM4ECYP3A4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748806-A1 | BIOCOMPATIBLE POLYACRYLATE COMPOSITIONS FOR MEDICAL APPLICATIONS | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2007-02-07 | — | — | EP | claimed |
| WO-2005097227-A1 | BIOCOMPATIBLE POLYACRYLATE COMPOSITIONS FOR MEDICAL APPLICATIONS | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2005-10-20 | — | — | WO | claimed |
| EP-1748806-A1 | BIOCOMPATIBLE POLYACRYLATE COMPOSITIONS FOR MEDICAL APPLICATIONS | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005097227-A1 | BIOCOMPATIBLE POLYACRYLATE COMPOSITIONS FOR MEDICAL APPLICATIONS | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2005-10-20 | — | — | WO | disclosed |