Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 15/20 | 0.49 |
| ▸ | ACHE | P22303 | 15/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5393266 | 0.87 | MAPT (0.45) | BCHEACHETP53MAPTSMN1; SMN2 | |
| SCHEMBL5324226 | 0.87 | BCHE (0.42) | BCHEACHETP53MAPTSMN1; SMN2 | |
| SCHEMBL5320742 | 0.87 | BCHE (0.42) | BCHEACHEMAPTSMN1; SMN2 | |
| SCHEMBL5324947 | 0.84 | MAPT (0.45) | MTNR1AMTNR1BBCHEACHEMAPT | |
| SCHEMBL5324213 | 0.83 | KDM4E (0.41) | BCHEACHEMAPTSMN1; SMN2 | |
| SCHEMBL3594182 | 0.82 | SMN1; SMN2 (0.61) | MTNR1ABCHEACHEMAPTSMN1; SMN2 | |
| SCHEMBL5321150 | 0.82 | KMT2A (0.39) | BCHEACHEMAPTSMN1; SMN2 | |
| SCHEMBL5324261 | 0.81 | BCHE (0.39) | BCHEACHEMAPTSMN1; SMN2 | |
| SCHEMBL3591679 | 0.80 | KMT2A (0.41) | BCHEACHEMAPTSMN1; SMN2 | |
| SCHEMBL5322576 | 0.80 | POLB (0.40) | BCHEACHEMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115231-A2 | CXCR4 MODULATORS | CHEMOCENTRYX, INC. (US) | 2007-10-11 | — | — | WO | disclosed |