Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 10/20 | 0.41 |
| ▸ | ACHE | P22303 | 10/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321150 | 0.92 | KMT2A (0.39) | MAPTNPSR1GAATSHRALDH1A1 | |
| SCHEMBL5324261 | 0.90 | BCHE (0.39) | MAPTNPSR1GAATSHRALDH1A1 | |
| SCHEMBL5321296 | 0.88 | MCOLN3 (0.39) | MAPTGAATSHRALDH1A1LMNA | |
| SCHEMBL5322576 | 0.88 | POLB (0.40) | MAPTGAATSHRALDH1A1LMNA | |
| SCHEMBL5324226 | 0.87 | BCHE (0.42) | MAPTGAATSHRALDH1A1LMNA | |
| SCHEMBL5393266 | 0.87 | MAPT (0.45) | MAPTTSHRALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5320742 | 0.86 | BCHE (0.42) | MAPTALDH1A1LMNASMN1; SMN2BCHE | |
| SCHEMBL5324241 | 0.84 | MTNR1A (0.51) | MAPTSMN1; SMN2BCHEACHEMTNR1A | |
| SCHEMBL3594182 | 0.83 | SMN1; SMN2 (0.61) | MAPTGAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5324213 | 0.83 | KDM4E (0.41) | MAPTALDH1A1LMNASMN1; SMN2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115231-A2 | CXCR4 MODULATORS | CHEMOCENTRYX, INC. (US) | 2007-10-11 | — | — | WO | disclosed |