Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330704 | 0.89 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTMAPK1HCRTR1TP53 | |
| SCHEMBL5328510 | 0.85 | CYP3A4 (0.36) | CYP3A4CYP2C9KMT2ACYP1A2CYP2D6 | |
| SCHEMBL5558310 | 0.79 | MAPT (0.39) | SMN1; SMN2MAPTMAPK1HCRTR1TP53 | |
| SCHEMBL5327618 | 0.77 | GLA (0.38) | MAPTRAB9ACYP3A4CYP2C9MEN1 | |
| SCHEMBL4574357 | 0.76 | KDM4E (0.44) | SMN1; SMN2MAPTMAPK1HCRTR1TP53 | |
| SCHEMBL5563484 | 0.76 | KMT2A (0.39) | SMN1; SMN2MAPTMAPK1HCRTR1TP53 | |
| Bicarbonate SCHEMBL5984921 | 0.76 | GLA (0.37) | RAB9ACYP3A4CYP2C9MEN1KMT2A | |
| Iodide SCHEMBL5323160 | 0.76 | KMT2A (0.38) | SMN1; SMN2MAPTMAPK1HCRTR1TP53 | |
| SCHEMBL5329533 | 0.73 | CYP3A4 (0.36) | SMN1; SMN2MAPTTP53RAB9ATSHR | |
| SCHEMBL4735946 | 0.73 | ELANE (0.40) | MAPTMAPK1TP53RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007141253-A1 | PROCESS FOR THE PRODUCTION OF INTERMEDIATES FOR THE PREPARATION OF TRICYCLIC IMIDAZOPYRIDINES | NYCOMED GMBH (DE) | 2007-12-13 | — | — | WO | disclosed |