Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4994479 | 0.89 | KMT2A (0.36) | GLAHSD11B1HPGDALDH1A1RAB9A | |
| SCHEMBL5330704 | 0.88 | SMN1; SMN2 (0.43) | HPGDALDH1A1HSD17B10KDM4ERAB9A | |
| Bicarbonate SCHEMBL4976269 | 0.88 | KMT2A (0.35) | GLAHSD11B1HPGDALDH1A1RAB9A | |
| SCHEMBL5559185 | 0.86 | KMT2A (0.42) | HPGDALDH1A1HSD17B10KDM4ERAB9A | |
| Formic Acid SCHEMBL4976263 | 0.86 | HSD11B1 (0.34) | GLAHSD11B1HPGDALDH1A1RAB9A | |
| SCHEMBL5328503 | 0.85 | ADRA1D (0.40) | RAB9ANPC1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL4977670 | 0.80 | P2RX3 (0.36) | GLAHPGDALDH1A1HSD17B10KDM4E | |
| SCHEMBL5035217 | 0.78 | ALDH1A1 (0.38) | GLAHSD11B1HPGDALDH1A1RAB9A | |
| SCHEMBL5327607 | 0.77 | HSD11B1 (0.35) | GLAHSD11B1ALDH1A1HSD17B10RAB9A | |
| SCHEMBL5566421 | 0.76 | HSD11B1 (0.37) | HSD11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007141253-A1 | PROCESS FOR THE PRODUCTION OF INTERMEDIATES FOR THE PREPARATION OF TRICYCLIC IMIDAZOPYRIDINES | NYCOMED GMBH (DE) | 2007-12-13 | — | — | WO | disclosed |
| EP-1697358-A1 | INTERMEDIATES FOR THE PREPARATION OF TRICYCLIC DIHYDROPYRANO -IMIDAZO -PYRIDINES DERIVATIVES | Altana Pharma AG (DE) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005058894-A1 | INTERMEDIATES FOR THE PREPARATION OF TRICYCLIC DIHYDROPYRANO -IMIDAZO -PYRIDINES DERIVATIVES | ALTANA PHARMA AG (DE) | 2005-06-30 | — | — | WO | disclosed |