Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 6/20 | 0.49 |
| ▸ | CCKBR | P32239 | 14/20 | 0.43 |
| ▸ | CCKAR | P32238 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320256 | 0.89 | PTH1R (0.65) | PTH1RCCKBRCCKAR | |
| SCHEMBL5394847 | 0.83 | PTH1R (0.51) | PTH1RCCKBRCCKAR | |
| SCHEMBL5324687 | 0.81 | PTH1R (0.46) | PTH1RCCKBRCCKAR | |
| SCHEMBL5324678 | 0.81 | PTH1R (0.43) | PTH1RCCKBRCCKAR | |
| SCHEMBL5324849 | 0.81 | PTH1R (0.55) | PTH1RCCKBRCCKAR | |
| SCHEMBL5326149 | 0.79 | PTH1R (0.54) | PTH1RCCKBRCCKAR | |
| SCHEMBL5320516 | 0.77 | PTH1R (0.55) | PTH1RCCKBRCCKAR | |
| SCHEMBL5285926 | 0.76 | PTH1R (0.69) | PTH1RCCKBRCCKAR | |
| SCHEMBL5285139 | 0.76 | PTH1R (0.49) | PTH1RCCKBRCCKAR | |
| SCHEMBL3916397 | 0.76 | CCKBR (0.55) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006129120-A9 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-03-22 | — | — | WO | disclosed |
| WO-2006129120-A2 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2006-12-07 | — | — | WO | disclosed |