Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.50 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322023 | 0.89 | CYP2A6 (0.51) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL5580227 | 0.85 | SLC7A5 (0.54) | GRIA2SLC7A5PTGS1KDM4EUSP2 | |
| SCHEMBL5320165 | 0.76 | CYP1A2 (0.55) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL16704739 | 0.75 | GRIA2 (0.54) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL17194110 | 0.75 | GRIA2 (0.54) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL31370182 | 0.74 | CYP2A6 (0.54) | GRIA2SLC7A5PTGS1KDM4EUSP2 | |
| SCHEMBL5322815 | 0.74 | CYP2A6 (0.54) | GRIA2SLC7A5PTGS1KDM4EUSP2 | |
| SCHEMBL6544511 | 0.73 | PTGS1 (0.47) | MRGPRX4PTGS1KDM4EHIF1AHSD17B10 | |
| SCHEMBL3810731 | 0.73 | KDM4E (0.44) | MRGPRX4KDM4ETDP1PTGER4PTGER3 | |
| SCHEMBL12569411 | 0.73 | CYP2A6 (0.52) | PTGS1KDM4EALOX15HTR2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070258899-A1 | Diagnostic and therapeutic agents | KARYON-CTT LTD (FI) | 2007-11-08 | — | — | US | disclosed |
| WO-2007113385-A1 | DIAGNOSTIC AND THERAPEUTIC AGENTS | KARYON-CTT LTD (FI) | 2007-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070258899-A1 | Diagnostic and therapeutic agents | YBX1, MLX, TPX2 | GRIK1 4162/4885GRIA1 3993/4885GRIA2 4396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.