Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 7/20 | 0.67 |
| ▸ | COMT | P21964 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.67 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.67 |
| ▸ | EGFR | P00533 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.41 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.41 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324825 | 1.00 | FTO (0.67) | FTOCOMTMEN1KMT2AABCC3 | |
| SCHEMBL4941843 | 0.93 | FTO (0.65) | FTOCOMTMEN1KMT2AABCC3 | |
| SCHEMBL4941789 | 0.93 | FTO (0.65) | FTOCOMTMEN1KMT2AABCC3 | |
| SCHEMBL4933461 | 0.92 | FTO (0.75) | FTOCOMTMEN1KMT2AABCC3 | |
| SCHEMBL4943265 | 0.92 | FTO (0.66) | FTOCOMTMEN1KMT2AABCC3 | |
| SCHEMBL4943255 | 0.92 | FTO (0.66) | FTOCOMTMEN1KMT2AABCC3 | |
| SCHEMBL14345844 | 0.92 | FTO (0.66) | FTOCOMTMEN1KMT2AABCC3 | |
| SCHEMBL5323630 | 0.92 | FTO (0.71) | FTOCOMTMEN1KMT2AABCC3 | |
| SCHEMBL5323628 | 0.92 | FTO (0.71) | FTOCOMTMEN1KMT2AABCC3 | |
| SCHEMBL4938761 | 0.91 | FTO (0.63) | FTOCOMTMEN1KMT2AABCC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007144169-A2 | ENTACAPONE-DERIVATIVES | SCHWARZ PHARMA AG (DE) | 2007-12-21 | — | — | WO | disclosed |