Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5814478 | 0.89 | CHRM3 (0.66) | CHRM3 | |
| SCHEMBL3138470 | 0.88 | CHRM3 (0.61) | CHRM3 | |
| SCHEMBL3142620 | 0.88 | CHRM3 (0.61) | CHRM3 | |
| SCHEMBL5285760 | 0.85 | CHRM3 (0.62) | CHRM3 | |
| SCHEMBL3137874 | 0.84 | CHRM3 (0.56) | CHRM3 | |
| SCHEMBL3138322 | 0.83 | CHRM3 (0.54) | CHRM3 | |
| SCHEMBL3134489 | 0.82 | CHRM3 (0.54) | CHRM3 | |
| SCHEMBL5285440 | 0.82 | CHRM3 (0.58) | CHRM3 | |
| SCHEMBL3146872 | 0.81 | CHRM3 (0.57) | CHRM3 | |
| SCHEMBL3538495 | 0.80 | CHRM3 (0.54) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866284-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | Theravance, Inc. (US) | 2007-12-19 | — | — | EP | claimed |
| WO-2006099167-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE, INC. (US) | 2006-09-21 | — | — | WO | claimed |