Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 14/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15226075 | 0.83 | EPHX1 (0.55) | EPHX1NPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16710276 | 0.82 | EPHX1 (0.54) | EPHX1NPSR1NPC1RAB9ASMN1; SMN2 | |
| Bicarbonate SCHEMBL15225614 | 0.81 | EPHX1 (0.53) | EPHX1NPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12323565 | 0.76 | EPHX1 (0.50) | EPHX1NPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5330191 | 0.75 | EPHX2 (0.51) | EPHX1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2802318 | 0.74 | EPHX1 (0.60) | EPHX1NPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14919674 | 0.74 | DRD2 (0.50) | EPHX1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL20350198 | 0.74 | EPHX1 (0.60) | EPHX1NPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8393517 | 0.74 | EPHX1 (0.60) | EPHX1NPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17342574 | 0.74 | EPHX1 (0.59) | EPHX1NPSR1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007146086-A1 | CREATINE PRODRUGS, COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2007-12-21 | — | — | WO | disclosed |