Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12792113 | 0.82 | CCNE2 (0.41) | MAPTGAAHTTGPR55 | |
| SCHEMBL12792077 | 0.82 | CCNE2 (0.41) | MAPTGAAHTTGPR55 | |
| SCHEMBL3084379 | 0.82 | CA1 (0.33) | HTTNPSR1 | |
| SCHEMBL13138600 | 0.82 | ADORA2A (0.36) | MAPTCYP1A2CYP2C9CYP2C19ADORA2A | |
| SCHEMBL5325182 | 0.80 | CNR1 (0.40) | MAPTADORA2AADORA1HTTNPSR1 | |
| SCHEMBL3076140 | 0.79 | ADORA2A (0.41) | MAPTADORA2AADORA1PDE4APDE4C | |
| SCHEMBL3071096 | 0.77 | SALL4 (0.40) | MAPTGAAHTTNPSR1 | |
| SCHEMBL3072846 | 0.76 | GAA (0.33) | GAAHTTNPSR1GPR55 | |
| SCHEMBL635407 | 0.76 | MAPT (0.49) | MAPTCYP1A2CYP2C9CYP2C19ADORA2A | |
| SCHEMBL29560409 | 0.76 | MAPT (0.49) | MAPTCYP1A2CYP2C9CYP2C19ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773853-A1 | MONOPHOSPHINE COMPOUNDS, TRANSITION METAL COMPLEXES THEREOF AND PRODUCTION OF OPTICALLY ACTIVE COMPOUNDS USING THE COMPLEXES AS ASYMMETRIC CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2007-04-18 | — | — | EP | disclosed |
| WO-2005121157-A1 | MONOPHOSPHINE COMPOUNDS, TRANSITION METAL COMPLEXES THEREOF AND PRODUCTION OF OPTICALLY ACTIVE COMPOUNDS USING THE COMPLEXES AS ASYMMETRIC CATALYSTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-12-22 | — | — | WO | disclosed |