Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29560409 | 1.00 | MAPT (0.49) | MAPTWDR5DNMT1CES1RAB9A | |
| SCHEMBL12111893 | 0.93 | MAPT (0.46) | MAPTWDR5DNMT1CES1RAB9A | |
| SCHEMBL7518681 | 0.93 | MAPT (0.42) | MAPTWDR5DNMT1CES1RAB9A | |
| SCHEMBL27796343 | 0.93 | MAPT (0.63) | MAPTRAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL23581680 | 0.92 | MAPT (0.41) | MAPTWDR5DNMT1CES1RAB9A | |
| SCHEMBL9405037 | 0.91 | HSP90AA1 (0.41) | MAPTWDR5ALDH1A1MEN1KMT2A | |
| SCHEMBL31498197 | 0.91 | MAPT (0.41) | MAPTWDR5DNMT1CES1RAB9A | |
| SCHEMBL3811084 | 0.90 | MAPT (0.43) | MAPTWDR5DNMT1CES1RAB9A | |
| SCHEMBL25024158 | 0.90 | MAPT (0.39) | MAPTWDR5DNMT1CES1RAB9A | |
| SCHEMBL7799372 | 0.89 | MAPT (0.38) | MAPTWDR5DNMT1CES1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771812-B1 | Method for producing an optically active diphosphine | TAKASAGO PERFUMERY CO LTD (JP) | 2003-12-10 | — | — | EP | claimed |
| EP-0839819-A1 | Method of preparing optically active diphosphine ligands | Takasago International Corporation (JP) | 1998-05-06 | — | — | EP | claimed |
| US-5693868-A | REACTING 2,2'-BIS(TRIFLUOROMETHANESULFONYLOXY)-1,1-BINAPHTHYL WITH A PHOSPHINE OXIDE IN THE PRESENCE OF A TRANSITION METAL-PHOSPHINE COMPLEX | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1997-12-02 | — | — | US | claimed |
| EP-0771812-A1 | Method for producing an optically active diphosphine | Takasago International Corporation (JP) | 1997-05-07 | — | — | EP | claimed |
| JP-9124669-A | — | — | None | — | — | JP | disclosed |
| US-11500247-B2 | Liquid crystal sensor | PLATYPUS TECHNOLOGIES, LLC (US) | 2022-11-15 | — | — | US | disclosed |
| EP-3421449-B1 | PRODUCTION METHOD FOR 1,1'-BINAPHTHYL DERIVATIVES | UNIV KYOTO (JP) | 2021-03-31 | — | — | EP | disclosed |
| EP-3037398-B1 | METHOD FOR MANUFACTURING CHEMICAL COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2021-03-10 | — | — | EP | disclosed |
| US-20200409221-A1 | LIQUID CRYSTAL SENSOR | PLATYPUS TECHNOLOGIES, LLC | 2020-12-31 | — | — | US | disclosed |
| US-10717809-B2 | Production method of polymer compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-07-21 | — | — | US | disclosed |
| US-10611714-B2 | Method for producing 1,1′-binaphthyl derivatives and 1,1′-binaphthyl derivatives | KYOTO UNIVERSITY (JP) | 2020-04-07 | — | — | US | disclosed |
| US-20190185613-A1 | PRODUCTION METHOD OF POLYMER COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2019-06-20 | — | — | US | disclosed |
| EP-0754696-A1 | Chiral unsymmetric diphosphine compounds and transition metal complexes containing them as ligands | Takasago International Corporation (JP) | 1997-01-22 | — | — | EP | disclosed |
| EP-0732337-A1 | Optically active asymmetric diphosphine and process for producing optically active substance in its presence | Takasago International Corporation (JP) | 1996-09-18 | — | — | EP | disclosed |
| US-5530150-A | HAVING PHOSPHINE AND PHOSPHITE GROUPS IN SAME MOLECULE; CATALYST SELECTIVITY | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1996-06-25 | — | — | US | disclosed |
| EP-0684249-A1 | Phosphine compounds, complexes containing the phosphine compounds as ligands, and process for producing optically active aldehydes using the phosphine compounds or complexes | Takasago International Corporation (JP) | 1995-11-29 | — | — | EP | disclosed |
| EP-0684230-A1 | 4- (R)-1'-formylethyl azetidin-2-one derivatives | Takasago International Corporation (JP) | 1995-11-29 | — | — | EP | disclosed |
| EP-0614870-A2 | Process for producing optically active aldehydes | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1994-09-14 | — | — | EP | disclosed |
| EP-0614901-A1 | Phosphine compound and transition metal-phosphine complex containing the same as ligand | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1994-09-14 | — | — | EP | disclosed |
| EP-0614903-A2 | Phosphine compounds, complexes containing the phosphine compounds as ligands, process for producing optically active aldehydes using the phosphine compounds, or complexes, and 4-[(R)-1' formylethyl]azetidin-2-one derivatives | Takasago International Corporation (JP) | 1994-09-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10611714-B2 | Method for producing 1,1′-binaphthyl derivatives and 1,1′-binaphthyl derivatives | KYAT1, HAO2, MBOAT1 | MAPT 3357/4885WDR5 4474/4885DNMT1 1215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.