Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325030 | 0.91 | PTGDR2 (0.57) | SLC2A1PTGDR2MRGPRX4AKR1B1MAPT | |
| SCHEMBL14419541 | 0.87 | PTGDR2 (0.56) | SLC2A1PTGDR2MRGPRX4KCNH2CYP2C9 | |
| SCHEMBL14201809 | 0.83 | POLB (0.52) | SLC2A1MRGPRX4MAPT | |
| SCHEMBL14397344 | 0.81 | PTGDR2 (0.44) | PTGDR2MAPTTDP1TSHRTP53 | |
| SCHEMBL14419689 | 0.81 | PTGDR2 (0.54) | SLC2A1PTGDR2MRGPRX4AKR1B1MAPT | |
| SCHEMBL12328443 | 0.81 | PTGDR2 (0.54) | SLC2A1PTGDR2MRGPRX4AKR1B1MAPT | |
| SCHEMBL6931984 | 0.78 | SLC2A1 (0.65) | SLC2A1KCNH2MAPTCYP2C9TP53 | |
| SCHEMBL5627237 | 0.78 | PTGDR2 (0.57) | PTGDR2MAPTTDP1CYP2C9TP53 | |
| SCHEMBL14419687 | 0.78 | SLC2A1 (0.46) | SLC2A1PTGDR2MRGPRX4KCNH2MAPT | |
| SCHEMBL4581330 | 0.78 | SLC2A1 (0.48) | SLC2A1PTGDR2MRGPRX4KCNH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007121415-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007121418-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007121416-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-25 | — | — | WO | disclosed |