Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933170 | 0.90 | SLC2A1 (0.68) | SLC2A1KCNH2TP53MAPTSMN1; SMN2 | |
| SCHEMBL6933529 | 0.84 | SLC2A1 (0.57) | SLC2A1KCNH2TP53MAPTSMN1; SMN2 | |
| SCHEMBL5623473 | 0.84 | SLC2A1 (0.65) | SLC2A1KCNH2TP53MAPTSMN1; SMN2 | |
| SCHEMBL30601627 | 0.84 | SLC2A1 (0.65) | SLC2A1KCNH2TP53MAPTSMN1; SMN2 | |
| SCHEMBL5891717 | 0.82 | SLC2A1 (0.63) | SLC2A1KCNH2TP53MAPTSMN1; SMN2 | |
| SCHEMBL6933526 | 0.82 | SLC2A1 (0.68) | SLC2A1KCNH2TP53MAPTSMN1; SMN2 | |
| SCHEMBL5891404 | 0.82 | SLC2A1 (0.62) | SLC2A1KCNH2TP53MAPTSMN1; SMN2 | |
| Gw-695634 SCHEMBL29403521 | 0.81 | SLC2A1 (0.61) | SLC2A1KCNH2TP53MAPTSMN1; SMN2 | |
| Gw-695634 SCHEMBL5891791 | 0.81 | SLC2A1 (0.61) | SLC2A1KCNH2TP53MAPTSMN1; SMN2 | |
| Gw-695634 SCHEMBL5891100 | 0.81 | SLC2A1 (0.61) | SLC2A1KCNH2TP53MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363877-A2 | BENZOPHENONES AS INHIBITORS OF REVERSE TRANSCRIPTASE | SmithKline Beecham Corporation (US) | 2003-11-26 | — | — | EP | claimed |
| WO-2002070470-A2 | BENZOPHENONES AS INHIBITORS OF REVERSE TRANSCRIPTASE | SMITHKLINE BEECHAM CORPORATION (US) | 2002-09-12 | — | — | WO | claimed |
| EP-1363877-A2 | BENZOPHENONES AS INHIBITORS OF REVERSE TRANSCRIPTASE | SmithKline Beecham Corporation (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002070470-A2 | BENZOPHENONES AS INHIBITORS OF REVERSE TRANSCRIPTASE | SMITHKLINE BEECHAM CORPORATION (US) | 2002-09-12 | — | — | WO | disclosed |