SCHEMBL532550

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL531854	0.93	PARP1 (0.69)	PARP1HTR2BAKT1ALDH1A1BRD4
	SCHEMBL531908	0.82	HTR2B (0.55)	PARP1HTR2BAKT1ALDH1A1BRD4
	SCHEMBL531589	0.82	PARP1 (1.00)	PARP1DRD2DRD4DRD3
	SCHEMBL531863	0.79	PARP1 (0.59)	PARP1TSHRDRD2DRD4DRD3
	SCHEMBL2123056	0.79	PARP1 (0.90)	PARP1DRD2DRD4DRD3
	SCHEMBL2123061	0.79	PARP1 (0.90)	PARP1DRD2DRD4DRD3
	SCHEMBL2124744	0.79	PARP1 (0.75)	PARP1DRD2DRD4DRD3
	SCHEMBL15500316	0.78	PARP1 (0.81)	PARP1DRD2DRD4DRD3
	SCHEMBL10260145	0.77	PARP1 (0.83)	PARP1DRD2DRD4DRD3
	SCHEMBL2122266	0.76	PARP1 (0.81)	PARP1DRD2DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.