SCHEMBL531908

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL531854	0.90	PARP1 (0.69)	HTR2BPARP1AKT1ALDH1A1PAX8
	SCHEMBL2122948	0.82	PARP1 (0.78)	PARP1KDM4E
	SCHEMBL532550	0.82	PARP1 (0.69)	HTR2BPARP1AKT1ALDH1A1PAX8
	SCHEMBL2120506	0.79	PARP1 (0.59)	PARP1KDM4E
	SCHEMBL532570	0.77	PARP1 (0.67)	PARP1KDM4E
	SCHEMBL531863	0.74	PARP1 (0.59)	PARP1TSHR
	SCHEMBL531824	0.73	PARP1 (0.46)	PARP1TSHR
	SCHEMBL2124311	0.73	PARP1 (0.54)	PARP1ALDH1A1KDM4E
	SCHEMBL532673	0.72	PARP1 (0.56)	PARP1KDM4E
	SCHEMBL26314224	0.72	PARP1 (0.51)	PARP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.