Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15485534 | 0.85 | HRH3 (0.61) | MAPTHRH3HRH1SIGMAR1ATM | |
| SCHEMBL15740982 | 0.82 | HRH3 (0.56) | MAPTHRH3SIGMAR1 | |
| SCHEMBL15485592 | 0.80 | HRH3 (0.52) | MAPTHRH3SIGMAR1 | |
| SCHEMBL5281401 | 0.78 | HRH3 (0.62) | HRH3SLC6A2HRH1CHRM2ADRA2C | |
| SCHEMBL21037024 | 0.78 | HRH3 (0.62) | MAPTHRH3SLC6A2HRH1CHRM2 | |
| SCHEMBL7346055 | 0.78 | HRH3 (0.55) | MAPTHRH3SLC6A2HRH1CHRM2 | |
| SCHEMBL24059343 | 0.78 | HRH3 (0.60) | HRH3SLC6A2HRH1CHRM2ADRA2C | |
| SCHEMBL8361918 | 0.78 | HRH3 (0.60) | HRH3SLC6A2HRH1CHRM2ADRA2C | |
| SCHEMBL7887990 | 0.78 | HRH3 (0.60) | HRH3SLC6A2HRH1CHRM2ADRA2C | |
| SCHEMBL5327291 | 0.77 | HRH3 (0.44) | MAPTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827423-B1 | FUNCTIONALIZED CHAIN EXTENDED INITIATORS FOR ANIONIC POLYMERIZATION | FMC CORP (US) | 2007-12-12 | — | — | EP | claimed |