Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.54 |
| ▸ | HTR2A | P28223 | 5/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | MPO | P05164 | 2/20 | 0.40 |
| ▸ | TPO | P07202 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21446971 | 0.85 | SLC6A4 (0.52) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL5252357 | 0.82 | CES2 (0.48) | SLC6A4HTR2AKCNH2CYP3A4CYP2D6 | |
| SCHEMBL13452580 | 0.81 | SLC6A4 (0.47) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL13840653 | 0.81 | SLC6A4 (0.54) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL4244859 | 0.80 | SLC6A4 (0.63) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL17670630 | 0.80 | SLC6A4 (0.52) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL25375435 | 0.79 | SLC6A4 (0.55) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL12593467 | 0.79 | CES2 (0.50) | CYP3A4CYP2D6CES2MPOSRD5A2 | |
| SCHEMBL9120134 | 0.78 | IDO1 (0.53) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL8883258 | 0.76 | CES2 (0.47) | CYP3A4CYP2D6CES2MPOSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135527-A2 | BENZIMIDAZOLYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | disclosed |