Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 3/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | FGB | P02675 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4886587 | 0.80 | BCHE (0.42) | L3MBTL1HTR1A | |
| SCHEMBL14294239 | 0.74 | CYP1A2 (0.39) | MAPK1SMN1; SMN2MAPTCYP1A2CYP2C9 | |
| SCHEMBL22588357 | 0.71 | ALDH1A1 (0.55) | IDO1ALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL11208196 | 0.68 | MAPK1 (0.58) | TTRALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL954720 | 0.66 | ABCG2 (0.46) | ALDH1A1MAPK1SMN1; SMN2POLBMAPT | |
| SCHEMBL5326968 | 0.66 | MAOB (0.44) | ALDH1A1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL21295328 | 0.65 | CYP1A2 (0.45) | IDO1TTREP300KAT8ALDH1A1 | |
| SCHEMBL16096880 | 0.65 | TTR (0.51) | TTRALDH1A1KMT2AMAPK1RAB9A | |
| SCHEMBL10766141 | 0.65 | CYP1A2 (0.52) | TTRALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Diphenylether SCHEMBL28298596 | 0.65 | ALDH1A1 (0.75) | IDO1ALDH1A1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007134421-A1 | 2-VINYL INDOLES, PYRIDO AND AZEPINO INDOLE DERIVATIVES, 2-ALKYNYL INDOLES, 2-ALKYNYL BENZO[b]FURANS, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2007-11-29 | — | — | WO | disclosed |