Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 4/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | BCL6 | P41182 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5326148 | 0.88 | CDK2 (0.43) | CDK2CHEK1CCNA2CCNA1CSNK2A1 | |
| SCHEMBL5320632 | 0.88 | CDK2 (0.41) | CDK2CHEK1CCNA2CCNA1MAPKAPK2 | |
| SCHEMBL5323444 | 0.87 | CDK2 (0.40) | CDK2CHEK1CCNA2CCNA1MAPKAPK2 | |
| SCHEMBL5321368 | 0.85 | CSNK2A1 (0.41) | CDK2CHEK1CCNA2CCNA1MAPKAPK2 | |
| SCHEMBL5329409 | 0.84 | KDM4E (0.32) | KDM4EHTT | |
| SCHEMBL5594559 | 0.81 | CSNK2A1 (0.43) | CDK2MAPKAPK2CSNK2A1ALDH1A1KDM4E | |
| SCHEMBL14423709 | 0.77 | BCL6 (0.38) | CDK2MAPKAPK2CSNK2A1KDM4EBCL6 | |
| SCHEMBL5323120 | 0.75 | TP53 (0.33) | ALDH1A1KDM4EHPGD | |
| SCHEMBL14463752 | 0.75 | CDK2 (0.54) | CDK2MAPKAPK2CSNK2A1ALDH1A1KDM4E | |
| SCHEMBL14423710 | 0.75 | AR (0.40) | CDK2MAPKAPK2CSNK2A1KDM4ECSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118844-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR CONTROLLING HARMFUL FUNGI AND COMPOSITIONS COMPRISING THEM | BASF SE (DE) | 2007-10-25 | — | — | WO | disclosed |