Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.38 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14463868 | 0.90 | CDK2 (0.47) | CDK2CSNK2A1PDE2AKDM4EALDH1A1 | |
| SCHEMBL14463738 | 0.84 | CDK2 (0.34) | CDK2 | |
| SCHEMBL5594559 | 0.81 | CSNK2A1 (0.43) | CDK2CSNK2A1PDE2AKDM4EALDH1A1 | |
| SCHEMBL5325823 | 0.75 | CDK2 (0.40) | CDK2CSNK2A1KDM4EALDH1A1HPGD | |
| SCHEMBL4693069 | 0.75 | PDE2A (0.41) | CDK2CSNK2A1PDE2AKDM4EALDH1A1 | |
| SCHEMBL5233667 | 0.75 | CCNT1 (0.32) | CDK2 | |
| SCHEMBL5325828 | 0.75 | CSNK2A1 (0.47) | CDK2CSNK2A1KDM4EALDH1A1HPGD | |
| SCHEMBL14463731 | 0.74 | CDK2 (0.42) | CDK2CSNK2A1PDE2AKDM4EALDH1A1 | |
| SCHEMBL4690562 | 0.74 | CDK2 (0.42) | CDK2CSNK2A1PDE2AKDM4EALDH1A1 | |
| SCHEMBL975954 | 0.74 | MAPK1 (0.38) | PDE2AALDH1A1HPGDMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513843-B1 | PYRAZOLOPYRIMIDINES AND THE USE THEREOF FOR CONTROLLING HARMFUL ORGANISMS | BAYER CROPSCIENCE AG (DE) | 2007-07-04 | — | — | EP | disclosed |