SCHEMBL5325916

SCHEMBL5325916

CN(C(=O)O)[C@@H]1CN(c2cc(F)c(N3CC(=NO[Si](C)(C)C(C)(C)C)C3)c(F)c2)C(=O)O1

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5326371 0.84 MAOA (0.43) MAOA
SCHEMBL5325709 0.84 MAOA (0.40) MAOA
SCHEMBL5370075 0.80 MAOA (0.50) MAOA
SCHEMBL5356103 0.79 MAOA (0.41) MAOA
SCHEMBL5328160 0.78 MAOA (0.47) MAOA
SCHEMBL5323611 0.78 MAOA (0.47) MAOA
SCHEMBL5329983 0.77 MAOA (0.44) MAOA
SCHEMBL5727240 0.75 MAOA (0.49) MAOA
SCHEMBL5329893 0.75 MAOA (0.42) MAOA
SCHEMBL5326903 0.75 MAOA (0.42) MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007004049-A1 OXAZOLIDINONES CONTAINING AZETIDINE AS ANTIBACTERIAL AGENTS PHARMACIA & UPJOHN COMPANY LLC (US) 2007-01-11 WO disclosed