Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 5/20 | 0.52 |
| ▸ | PIM2 | Q9P1W9 | 5/20 | 0.52 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 7/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.48 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781425 | 0.90 | MYC (0.53) | PIM1CISD1RAB9A | |
| SCHEMBL4781421 | 0.90 | MYC (0.53) | PIM1CISD1RAB9A | |
| SCHEMBL4775888 | 0.83 | PIM1 (0.50) | PIM1PIM2PIM3HPGDAKR1B1 | |
| SCHEMBL4775890 | 0.83 | PIM1 (0.50) | PIM1PIM2PIM3HPGDAKR1B1 | |
| SCHEMBL1247641 | 0.79 | PIM1 (0.54) | PIM1PIM2PIM3HPGDAKR1B1 | |
| SCHEMBL12891939 | 0.79 | PIM1 (0.54) | PIM1PIM2PIM3HPGDAKR1B1 | |
| SCHEMBL1247642 | 0.79 | PIM1 (0.54) | PIM1PIM2PIM3HPGDAKR1B1 | |
| SCHEMBL8148705 | 0.76 | MGAM (0.56) | PIM1PIM2PIM3HPGD | |
| SCHEMBL8148703 | 0.76 | MGAM (0.56) | PIM1PIM2PIM3HPGD | |
| SCHEMBL5320923 | 0.74 | CISD1 (0.51) | PIM1CISD1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007119600-A1 | CARBAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-10-25 | — | — | WO | disclosed |