Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 4/20 | 0.33 |
| ▸ | MAOA | P21397 | 4/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325290 | 1.00 | CYP3A4 (0.38) | CYP3A4MAPK1HCRTR2HCRTR1ALDH1A1 | |
| SCHEMBL18176799 | 0.83 | CYP3A4 (0.39) | CYP3A4MAPK1HCRTR2HCRTR1ALDH1A1 | |
| SCHEMBL17827377 | 0.83 | CYP3A4 (0.39) | CYP3A4MAPK1HCRTR2HCRTR1ALDH1A1 | |
| SCHEMBL18176800 | 0.83 | CYP3A4 (0.39) | CYP3A4MAPK1HCRTR2HCRTR1ALDH1A1 | |
| SCHEMBL14626066 | 0.81 | CYP3A4 (0.42) | CYP3A4MAPK1HCRTR2HCRTR1ALDH1A1 | |
| SCHEMBL5331015 | 0.81 | CYP3A4 (0.42) | CYP3A4MAPK1HCRTR2HCRTR1ALDH1A1 | |
| SCHEMBL18801954 | 0.81 | CYP3A4 (0.42) | CYP3A4MAPK1HCRTR2HCRTR1ALDH1A1 | |
| SCHEMBL20537397 | 0.81 | CYP3A4 (0.38) | CYP3A4MAPK1HCRTR2HCRTR1ALDH1A1 | |
| SCHEMBL16808485 | 0.81 | CYP3A4 (0.42) | CYP3A4MAPK1HCRTR2HCRTR1ALDH1A1 | |
| SCHEMBL17821191 | 0.80 | CYP3A4 (0.48) | CYP3A4MAPK1HCRTR2HCRTR1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007005935-A2 | NOREPINEPHRINE TRANSPORTER RADIOTRACERS AND METHODS OF SYNTHESES THEREOF | MOLECULAR NEUROIMAGING, LLC (US) | 2007-01-11 | — | — | WO | disclosed |
| WO-2007005935-A2 | NOREPINEPHRINE TRANSPORTER RADIOTRACERS AND METHODS OF SYNTHESES THEREOF | MOLECULAR NEUROIMAGING, LLC (US) | 2007-01-11 | — | — | WO | disclosed |