Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4240413 | 0.88 | MME (0.42) | MMEHDAC9MAOAMAOB | |
| Hydrochloric Acid SCHEMBL4236278 | 0.86 | MME (0.41) | MMEHDAC9MAOAMAOB | |
| SCHEMBL8558010 | 0.79 | S1PR1 (0.41) | SIGMAR1MAOAMAOB | |
| SCHEMBL8554610 | 0.77 | SIGMAR1 (0.39) | SIGMAR1PARP1MAOAMAOB | |
| SCHEMBL8556517 | 0.77 | SIGMAR1 (0.39) | SIGMAR1PARP1MAOAMAOB | |
| SCHEMBL9583897 | 0.75 | SIGMAR1 (0.39) | SIGMAR1PARP1MAOAMAOB | |
| SCHEMBL29511535 | 0.74 | PARP1 (0.39) | SIGMAR1PARP1ALDH1A1HDAC9 | |
| SCHEMBL199421 | 0.74 | PARP1 (0.39) | SIGMAR1PARP1ALDH1A1HDAC9 | |
| SCHEMBL268919 | 0.74 | PARP1 (0.39) | SIGMAR1PARP1ALDH1A1HDAC9 | |
| SCHEMBL29410824 | 0.74 | PARP1 (0.39) | SIGMAR1PARP1ALDH1A1HDAC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396459-B1 | METHODS OF CREATING AND SCREENING DNA-ENCODED LIBRARIES | X-CHEM INC (US) | 2017-05-03 | — | — | EP | disclosed |
| WO-2007123686-A2 | DPP INHIBITORS AND USES THEREOF | POINT THERAPEUTICS, INC. (US) | 2007-11-01 | — | — | WO | disclosed |