SCHEMBL5326876

SCHEMBL5326876

SNc1n[nH]c2cncnc12

nearest known ligand 0.49

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 13/20 0.49
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11874314 0.75 GRM4 (0.39) GRM4
SCHEMBL15919225 0.73 GRM4 (0.52) GRM4CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL30132904 0.71 DYRK1A (0.52) GRM4CYP3A4
SCHEMBL29414359 0.71 GRM4 (0.39) GRM4
SCHEMBL421235 0.71 DYRK1A (0.52) GRM4CYP3A4
SCHEMBL352379 0.71 GRM4 (0.39) GRM4
SCHEMBL2619233 0.71 GRM4 (0.39) GRM4CYP1A2
SCHEMBL473390 0.71 GRM4 (0.46) GRM4
SCHEMBL473498 0.71 GRM4 (0.39) GRM4
SCHEMBL28270065 0.70 GRM4 (0.37) GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007101804-A1 SUBSTITUTED PYRAZOLOPYRIMIDINES, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF FOR CONTROLLING PARASITIC FUNGI AND AGENTS COMPRISING THE SAME BASF SE (DE) 2007-09-13 WO disclosed
WO-2007101859-A1 SUBSTITUTED PYRAZOLOPYRIMIDINES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF FOR CONTROLLING PARASITIC FUNGI AND AGENTS CONTAINING THE LATTER BASF SE (DE) 2007-09-13 WO disclosed