Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL421235 | 0.75 | DYRK1A (0.52) | GRM4 | |
| SCHEMBL30132904 | 0.75 | DYRK1A (0.52) | GRM4 | |
| SCHEMBL473498 | 0.75 | GRM4 (0.39) | GRM4MAPK14 | |
| SCHEMBL11874314 | 0.75 | GRM4 (0.39) | GRM4MAPK14 | |
| SCHEMBL473390 | 0.75 | GRM4 (0.46) | GRM4MAPK14 | |
| SCHEMBL545813 | 0.75 | GRM4 (0.39) | GRM4MAPK14 | |
| SCHEMBL2619233 | 0.75 | GRM4 (0.39) | GRM4MAPK14 | |
| SCHEMBL29414359 | 0.75 | GRM4 (0.39) | GRM4MAPK14 | |
| SCHEMBL325244 | 0.73 | HCAR2 (0.36) | GRM4 | |
| SCHEMBL5084942 | 0.72 | RPS6KB1 (0.38) | GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641800-B1 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2008-03-05 | — | — | EP | claimed |
| EP-1513843-B1 | PYRAZOLOPYRIMIDINES AND THE USE THEREOF FOR CONTROLLING HARMFUL ORGANISMS | BAYER CROPSCIENCE AG (DE) | 2007-07-04 | — | — | EP | claimed |
| WO-2007071686-A1 | COMPOSITION FOR DYEING KERATIN FIBRES WITH A TETRAAZAPENTAMETHINE CATIONIC DIRECT DYE, AN OXIDATION BASE AND A PARTICULAR COUPLER | L'ORÉAL (FR) | 2007-06-28 | — | — | WO | claimed |
| JP-2007506665-A | — | — | 2007-03-22 | — | — | JP | claimed |
| US-20060258685-A1 | Substituted pyrazolopyrimidines, methods for the production thereof, use of the same for controlling pathogenic fungi, and agents containing said compounds | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-16 | — | — | US | claimed |
| CN-1839136-A | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2006-09-27 | — | — | CN | claimed |
| US-20060089499-A1 | Pyrazolopyrimidines and the use thereof for controlling harmful organisms | UWW VENTURES UNLIMITED (GB) | 2006-04-27 | — | — | US | claimed |
| EP-1641800-A1 | PYRAZOLOPYRIMIDINES | Bayer CropScience AG (DE) | 2006-04-05 | — | — | EP | claimed |
| EP-1513843-A1 | PYRAZOLOPYRIMIDINES AND THE USE THEREOF FOR CONTROLLING HARMFUL ORGANISMS | Bayer CropScience AG (DE) | 2005-03-16 | — | — | EP | claimed |
| WO-2005000851-A1 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-01-06 | — | — | WO | claimed |
| US-20040231067-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses | L'OREAL (FR) | 2004-11-25 | — | — | US | claimed |
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| WO-2004000844-A1 | PYRAZOLOPYRIMIDINES AND THE USE THEREOF FOR CONTROLLING HARMFUL ORGANISMS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-12-31 | — | — | WO | claimed |
| CN-115279765-B | 1H-pyrazolo [4,3-d ] pyrimidine compounds as Toll-like receptor 7 (TLR 7) agonists | 百时美施贵宝公司 | 2024-11-12 | — | — | CN | disclosed |
| CN-115643805-B | 1H-pyrazolo [4,3-d ] pyrimidine compounds as Toll-like receptor 7 (TLR 7) agonists | 百时美施贵宝公司 | 2024-11-08 | — | — | CN | disclosed |
| US-20230348468-A1 | 1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS | BRISTOL-MYERS SQUIBB COMPANY | 2023-11-02 | — | — | US | disclosed |
| US-5436258-A | Prevention of bone resorption | ELI LILLY AND COMPANY (US) | 1995-07-25 | — | — | US | disclosed |
| EP-0587378-A1 | Prevention of bone resorption | ELI LILLY AND COMPANY (US) | 1994-03-16 | — | — | EP | disclosed |
| US-4654348-A | Pyrazolo[4,3-d]pyrimidine derivative, process for its production, antihyperlipidemic agent containing it, its intermediate, and process for the production of the intermediate | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1987-03-31 | — | — | US | disclosed |
| EP-0157415-A2 | Pyrazolo[4,3-d] pyrimidine derivative process for its production antihyperlipidemic agent containing it, its intermediate, and process for the production of the intermediate | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1985-10-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089499-A1 | Pyrazolopyrimidines and the use thereof for controlling harmful organisms | PRDX1, PRDX2, PRDX5 | GRM4 2668/4885MAPK14 3017/4885 |
| US-20060258685-A1 | Substituted pyrazolopyrimidines, methods for the production thereof, use of the same for controlling pathogenic fungi, and agents containing said compounds | CBR1, CBR3, AKR7A2 | GRM4 3146/4885MAPK14 4418/4885 |
| US-20230348468-A1 | 1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS | TLR7, TLR9, TLR1 | GRM4 287/4885MAPK14 697/4885 |
| US-20040231067-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses | KRT18, CDC73, PYCR1 | GRM4 3257/4885MAPK14 2471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.